RNA Details
Disease Name
liver cirrhosis
Tissue
liver
RNA Symbol
GALNAC
RNA ID
RNA Type
siRNA
Alteration Pattern
dysregulation
Species
mus musculus
Detection Methods
pharmacokinetic analysis; immunoblotting etc.
Target
GALNAC-SIRNA
Pathway
NA
PubMed ID
Title
Evaluation of GalNAc-siRNA Conjugate Activity in Pre-clinical Animal Models with Reduced Asialoglycoprotein Receptor Expression
Year
2018
Function
"Our data support a broad application of the galnac-sirna technology for hepatic targeting, including disease states where asgpr expression may be reduced."